Description
Tier 1: Basic Module Execution ($2,000)
The Goal: A high-fidelity “Clean Data” foundation ready for immediate biological interpretation.
- Timeline: 72-Hour Rapid Kickoff (approx. 1.5 work weeks for delivery).
- Best For: Standardized datasets (up to 25 samples) requiring a single, expert-led computational step.
- What’s Included:
- Specialized Execution: Focused delivery of one core task: e.g., Advanced QC/Filtering, Batch-Effect Correction, Differential Expression (DGE), or Dimensionality Reduction (UMAP/t-SNE).
- Literature-Backed Parameters: Expert selection of tool settings based on current peer-reviewed benchmarks—not just default settings.
- Visual Validation Suite: 3 diagnostic plots (e.g., PCA, Cook’s distance, or Silhouette scores) to verify data integrity.
- The Deliverable: A finalized, normalized data object (RDS/CSV) and a technical summary of the methodology used.
Tier 2: Premium Module for Complex Datasets ($5,000)
The Goal: “Reviewer-Proof” high-resolution insights from your most difficult or high-volume cohorts.
- Timeline: Priority Scheduling (approx. 3 work weeks for delivery).
- Best For: Large-scale cohorts (>25 samples), clinical trial data, or “noisy” samples (ultra-low input/rare cells) where standard pipelines fail.
- What’s Included:
- Custom Algorithmic Tuning: Development of bespoke normalization strategies to handle high noise-to-signal ratios and complex multi-batch integration.
- Iterative Sub-Clustering: Multi-stage refinement to identify rare subpopulations or subtle biological signals that “Basic” tools often overlook.
- Positive Control Validation: We run our internal “Gold Standard” datasets alongside yours to prove the module’s accuracy on your specific tissue type.
- The Deliverable: Integrated data objects, a suite of publication-ready discovery figures, and a Detailed Technical Narrative (Methods/Appendix) justifying every parameter choice for rigorous peer review.
